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The most cited single result is from Yun and colleagues in 2018, who showed that NLY01, a long-acting PEGylated GLP-1R agonist, blocked the microglia-driven conversion of resting astrocytes into the neurotoxic A1 phenotype in mouse models, a process implicated in neuronal death in both Parkinsons and Alzheimers disease [4]
Providers should document pain levels, functional limitations, and objective findings like spasm or decreased range of motion
Poor technique can denature the peptide, create foam that wastes product, or introduce contamination that ruins the entire vial
Week one is protected weight-bearing in a surgical boot
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