This is mainly because a lot of these formulations dont have preservatives or stabilizers to help keep them stable
1 Askarpour M, Hadi A, Miraghajani M, Symonds ME, Sheikhi A, Ghaedi E. Beneficial effects of L-carnitine supplementation for weight control in overweight and obese adults: an updated systematic review and dose-response meta-analysis of randomized controlled trials. Pharmacol Res. 2020 Jan;151:104554. doi: 10.1016/j.phrs.2019.104554. epub 2019 Nov 17. PMID: 31743774
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These results are promising, but it is important to understand that individual outcomes vary based on starting weight, diet, activity level, and adherence to treatment protocols