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Moreover, mRNA expression levels of NF-kB downstream targets, including Il1a , Il1b , Il6 , Mmp3 , Mmp9 , Ccl2 , Ccl4 , Bcl2 , Bcl2a1a and Ccnd2 , were downregulated in ESCC by BSO (Figure 5b)

Downregulation of TLR4/MyD88/p38MAPK and JAK/STAT pathway in RAW 264.7 cells by Alpinia galanga reveals its beneficial effects in inflammation

Long-term cardiovascular outcomes of COVID-19