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This anti-lipogenic activity is hypothesized to involve inhibition of acetyl-CoA carboxylase, the rate-limiting enzyme in de novo lipogenesis

This explains why many include a b12 shot for weight loss alongside treatments like fat burners or appetite suppressants, including semaglutide, to create a more complete approach

As with anything else, though, its best to understand a weight loss product completely before investing in it, especially when concentrated supplements are in the mix