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Based on metagenome-wide association studies, there were decreased abundances of some butyrate-producing bacteria and increased opportunistic pathogens in patients with T2D ( Interactions between gut microbiota and GLP-1 RA have been investigated in few animal models ( via a gut-brain axis ( Materials and Methods Participants Enrollment and Clinical Data Collection All participants ( n = 52) were enrolled from outpatient departments at the Taipei, Linkou and Taoyuan branches of Chang Gung Memorial Hospital, certified Diabetes Health Promotion Centers in Taiwan

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