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But because it reduces appetite, many people eat and drink less overall, and since roughly 20% of daily fluid comes from food, hydration can slip without you noticing

At a glance Drug / isotretinoin (Accutane), oral retinoid for severe nodular acne Supplement / omega-3 fatty acids (EPA + DHA), typically from fish oil or algae oil Primary interaction type / pharmacodynamic (lipid and platelet pathways), not pharmacokinetic Triglyceride effect / isotretinoin raises triglycerides in up to 44% of patients

One strength of our analysis is its focus on individuals newly initiated on GLP-1 RAs, minimising prescription bias

The World Anti-Doping Agency (WADA), which oversees prohibited substances for most international sports, has not banned GLP-1 medications