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-MSH binding to MC1R results in the activation of adenylyl cyclase, increasing the intracellular levels of cAMP and subsequently upregulating TYR, tyrosinase related protein-1 (TRP-1) and tyrosinase related protein-2 (TRP-2) expression

The results obtained demonstrated that the progression of the disease in patients treated with ALA is signicantly lower than that in untreated patients or those treated with choline esterase inhibitors

Should only be used under medical or dietic supervision