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Importance of Gradual Dosage Increase The rationale behind starting with a sub-therapeutic dose during the initial weeks is to allow your body to adapt to the medication and minimize gastrointestinal side effects

Patients should seek prompt medical guidance for severe or persistent vomiting, signs of dehydration, severe abdominal pain, fainting, symptoms of low blood sugar, inability to keep fluids down, worsening constipation with pain or bloating, or any symptom that feels unsafe

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Interestingly, working memory is considered to have a strong genetic component based on the DRD1 gene variants.[ref] DRD2 receptor: The DRD2 receptor is less abundant in the cerebral cortex than the DRD1 receptor, but it is abundant in other areas of the brain with dopaminergic neurons