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Seek immediate medical evaluation if swollen lymph nodes are accompanied by: Systemic symptoms : Unexplained fever, drenching night sweats, or unintentional weight loss (beyond expected tirzepatide-related weight reduction) Rapid enlargement : Lymph nodes that grow quickly over days to weeks Hard, fixed, or irregular nodes : Lymph nodes that feel firm, immobile, or matted together Size : Nodes larger than 1-2 cm (approximately half an inch to one inch) that persist beyond two weeks Location : Supraclavicular (above the collarbone) lymphadenopathy, which has higher association with serious pathology Associated symptoms : Difficulty breathing, swallowing, or persistent cough

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Foods rich in antioxidants, such as vitamins C and E, are recommendable, including oranges, strawberries, nuts, and seeds

The clinical trial compared the 7.2mg weekly regimen against both the 2.4mg once weekly dose and placebo, with all participants following lifestyle interventions