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Aconitase activity To evaluate a functional consequence of oxidative stress, the activity of the redox-sensitive enzyme, aconitase, was measured using the Aconitase Assay Kit (Cayman Chemical, Ann Arbor, MI, USA) following the manufacturer's instructions

Subsequent research revealed calreticulins mediating role: LPA (18:1) promotes CRT expression through LPAR1/3-ROS-eIF2 pathways, with CRT knockdown inhibiting VEGF-C induction and in vivo lymphatic vessel density (79)

Electrical stimulation may counter some of the negative effects of implantation, such as it can modulate inflammatory responses [388], but can implantation itself be additive and positively alter gene expression