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Kidney Dysfunction: In chronic kidney disease (CKD) or renal failure, the bodys ability to filter and excrete B12 may be compromised, leading to accumulation in the blood 8

AtMYB73 directly binds to the promoter region of the actin depolymerizing factors (ADF) gene, inhibiting its expression and hindering actin depolymerization in Arabidopsis thaliana , thereby altering the composition of the plant cytoskeleton (Wang et al., 2021c)

Amoodi HA, Mick PT, Shipp DB, Friesen LM, Nedzelski JM, Chen JM, Lin VY

GCL is composed of a heavy catalytic subunit (GCLC, MW ~ 73,000) and a light modifier (GCLM, MW ~ 30,000) subunit