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Leistner, C & Menke, A Hypothalamic-pituitary-adrenal axis and stress, in Sex Differences in Neurology and Psychiatry Handbook of Clinical Neurology 55-64 (2020), 175

Weight loss doseeffect analyses were performed according to the magnitude of body weight change during the trial confined to the semaglutide group, because the primary objective was to examine the effects of body weight change related to semaglutide treatment rather than spontaneous or other lifestyle-related weight changes (as in the placebo group), using both intention-to-treat (primary) and on-treatment approaches

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