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Mechanistic and therapeutic role of Drp1 in the pathogenesis of Alzheimers disease

Responses to emotional changes and reward stimuli are dependent on intact function of the salience network , within which the anterior insula, anterior cingulate cortex and amygdala, ventral tegmental area, and thalamus function together to segregate the most relevant and rewarding among internal and extra-personal stimuli in order to guide behavior

Studies show that inhibiting nicotinamide Nmethyltransferase (NNMT) enhances metabolic health by reducing adipose tissue accumulation, improving insulin sensitivity, and promoting better energy utilization