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Doxycycline Hyclate 100 mg Pharmacologic Category: Antibiotic, Tetracycline Derivative FDA-Approved Uses: Acne vulgaris Anthrax (Bacillus anthracis, bioterror) Amebiasis (Entamoeba histolytica) Sexually transmitted infections (Chlamydia trachomatis) Malaria prophylaxis Rickettsia infections Rocky Mountain spotted fever (Rickettsia rickettsii) Q fever (Coxiella burnetii) Typhus Common Off-Label Uses: Lyme disease (Borrelia bacteria) Community-acquired pneumonia Acute bacterial rhinosinusitis Skin and soft tissue infections due to Staph aureus Tularemia / Rabbit fever (bioterror) Plague (Yersinia pestis, bioterror) Typical Adult Dosing: Anthrax (bioterror), inhalation post-exposure prophylaxis: 100 mg (1 capsule) TWICE DAILY for 4260 days Some experts favor longer durations (34 months)