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Lean Muscle Mass: Important for metabolism, insulin sensitivity, and strength
However, a post hoc analysis of 234 patients with an NAFLD activity score (NAS) of more than 4 at baseline showed the significant resolution of NASH using a modified definition of response (19% in 120 mg elafibranor group and 9% in placebo, p =0.013)
But beyond this, forward-thinking work will ideally also improve comprehension of how the integrated network of nitrogen metabolism may contribute to such effects by sometimes-unexpected indirect mechanisms, and better distinguish between co-transmission and cell-autonomous metabolic effects
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