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The calculations were partly performed using the Research Center for Computational Science, Okazaki Research Facilities, National Institutes of Natural Sciences (NINS), Japan

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Lukashevich V, Del Prato S, Araga M, Kothny W (2014) Efficacy and safety of vildagliptin in patients with type 2 diabetes mellitus inadequately controlled with dual combination of metformin and sulphonylurea

conducted a pilot trial and demonstrated that one year of therapy with metformin improved the histological features of liver steatohepatitis (steatosis, inflammation and fibrosis), which was proven by biopsy [109]