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Drugs which inducecytochrome P450 3A4 (CYP 3A4) enzyme activity (e.g., barbiturates, phenytoin, carbamazepine, rifampin) may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased

Reduced Bone Density: Long-term smoking can reduce calcium absorption and bone mineral density, increasing the risk of vertebral fractures and spinal instability

All of those effects on the body add together to put smokers at a higher risk of many different medical conditions, including: Cancer Heart Disease Stroke COPD, Asthma Type 2 Diabetes Vascular Disease Eye Diseases Difficulties Conceiving (affecting both sexes) Reproductive health problems Birth Preterm Rheumatoid arthritis Smoking is a major risk factor for nearly every type of cancer

While youre riding that health kick of keeping fresh blood flowing through your body, check-in and make sure that you are maintaining a healthy high habit as well