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As a synthetic HGF mimetic, it forms a functional ligand by dimerizing with endogenous HGF to activate the HGF receptor and downstream signaling cascades

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Elizabetta Patorno, the study involved a large cohort of more than 200,000 medical records that specifically looked at the gastrointestinal side effects of semaglutide, tirzepatide and dulaglutide, the active ingredient in Trulicity, when used to treat type 2 diabetes

But while small molecules are likely to be cheaper to produce, Finer says its too early to project by how much