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Retrieved 26 September 2025

172 BuvatJ

Americian Journal of PhysiologyEndocrinology and Metabolism

On the supportive side, the foundational cell-culture work reported that the distinct E-domain of MGF inhibits terminal differentiation of myoblasts while increasing their proliferation a behavior opposite to that of mature IGF-1, and one that would fit the proposed role of expanding the precursor pool before differentiation