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As dynamic risk stratification has been used with clinical values in DTC, dynamic risk stratification for MTC was developed to modify initial risk estimation based on the response to therapy and biological tumor behavior, including change in serum calcitonin and CEA levels, and it has provided more useful real-time prognostic information than initial TNM staging [1416]

2 For breast cancers, increased BMI is an independent risk for cancer recurrence and poorer overall survival