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It's a starting point inherited from preclinical models that prioritized observable outcomes over dose efficiency
Importantly, treatment did not negatively impact markers such as bone mineral density (BMD) or body weight in a manner inconsistent with healthy controls (Fawcett 2010)
Sources: Sikiric et al., Curr Pharm Des 2018 | Chang et al., J Appl Physiol 2011 Security Profile & Chemical Identity Molecular specifications and preclinical safety data BPC-157 Chemical Identity Synthetic pentadecapeptide derived from human gastric juice BPC-157 Tolerance & Status Safety data from preclinical studies (rat, mouse, rabbit, dog) Published Preclinical Data 6 key studies published in J Orthop Res, J Appl Physiol, Curr Pharm Des, Growth Horm IGF Res and Am J Sports Med Biomechanics Significant improvement in tendon strength, stiffness and elasticity modulus at 14 days Achilles tendon repair (rat) Migration Dose-dependent acceleration of tendon fibroblast migration Tendon Repair Mechanisms Cytoprotection Novel cytoprotective mediator vascular recruitment and healing of the gastrointestinal tract Documented Gastroprotective Effects Important Notice Search Only Not intended for human consumption
The Tg gene is a crucial thyroid-specific antigen located on chromosome 8q24 and also in the bloodstream, which makes it a prime target for autoimmune reactions
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