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5 The measurement of cotinine--a primary metabolite of nicotine with a half-life of 16 to 18 hours that is detectable in urine, saliva, or serum--is a reliable method of determining use of or exposure to cigarettes or other tobacco products over a period of 2 to 3 days
59,60 Rats exposed to aerosol generated with a nickel-chromium alloy atomizer that was free of nicotine, vitamin E acetate, or tetrahydrocannabinol developed labored mouth breathing, decreased activity, and wheezing
This "epidemic" highlighted two aspects
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