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Phase 3 trials (SURMOUNT-1, SURMOUNT-2) showed that tirzepatide at 15 mg produces an average of 2022% body weight loss over 72 weeks, which translates to approximately 58 pounds monthly when averaged across the trial

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A small observational study reported that a brief period of fasting alone improved the signs and symptoms of psoriasis [18], and a 4 week low-energy diet improved the clinical severity of psoriasis independent of changes in weight loss [19]

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