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Philipose, et al., 'Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity - A Phase 2 Trial', N

2017 Feb;32(2):2115

It is unknown whether Ozempic causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined Ozempic is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

This is one of the most important facts in the entire comparison, because it means every ranking of the two is cross-trial inference, not a controlled result