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It acts directly on several target tissues, including skeletal muscle and bone, but several effects are mediated indirectly by circulating (liver-derived) or locally produced IGF-1

Participants received 30 or 60 mg/day of Q10 for 100 days, and serum samples were analyzed for Q10 concentrations, malondialdehyde, total antioxidant status, SOD, and glutathione peroxidase, using ELISA assays

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