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and 0.33g of compound 1 was dissolved in 100mL of acetonitrile, and then added dropwise to the above mixture to react at 0 to 5 for 3 hours, the resulting reaction solution was adjusted to pH 6.0 with phosphoric acid, and then 2 times of purified water was added, and centrifugation was carried out to obtain solid compound 2, the liquid chromatogram of FIG

In the SURMOUNT-1 trial, participants on the highest dose (15 mg) of tirzepatide lost an average of 20.9% of their body weight over 72 weeks

Key highlights Before first use, Ozempic should be refrigerated at 36F to 46F (2C to 8C)

By integrating semaglutide with personalized lifestyle modifications, including healthy eating and exercise, we can provide a holistic approach to weight management