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Treating LN and proteinuria with RAAS blockade at maximum tolerated doses is recommended, complemented with a sodium-poor diet to optimize its effect ( The evidence on RAAS inhibition in recent immunosuppression-based trials shows that treatment in terms of nephroprotection is usually poorly optimized before induction therapy is initiated

NP2 had a negative zeta potential of 8.88 mV and NP4 of 3.77 mV (Fig

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Rivera-Arconada I, Baccei ML, Lpez-Garca JA, Bardoni R (2025) An electrophysiologists guide to dorsal horn excitability and pain