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Mechanistically, GLP1RAs improve cardiac function by enhancing contractility and reducing myocardial injury 14,15,16 , exert vasodilatory and endothelial-protective effects, and display anti-inflammatory and anti-fibrotic actions that may limit adverse remodeling in heart failure (HF) 17

doi: 10.1016/S0140-6736(18)32261-X 87 GiuglianoDScappaticcioLLongoMCarusoPMaiorinoMIBellastellaGet al

More than a thousand GPs across the country received a letter on Friday, 7 March, from the Department of Health and Aged Care (DoHAC) raising concerns about their prescribing history of semaglutide